Evolutionary and functional analyses of LRP5 in archaic and extant modern humans

Abstract Background The human lineage has undergone a postcranial skeleton gracilization (i.e. lower bone mass and strength relative to body size) compared to other primates and archaic populations such as the Neanderthals. This gracilization has been traditionally explained by differences in the me...

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Hlavní autoři:	Neus Roca-Ayats, Iago Maceda, Carlos David Bruque, Núria Martínez-Gil, Natàlia Garcia-Giralt, Mónica Cozar, Leonardo Mellibovsky, Wim Van Hul, Oscar Lao, Daniel Grinberg, Susanna Balcells
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-05-01
Edice:	Human Genomics
Témata:	LRP5 Bone mineral density Neanderthal Denisovan Human evolution Archaic introgression
On-line přístup:	https://doi.org/10.1186/s40246-024-00616-6
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