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MicroRNA-219 loaded chitosan nanoparticles for treatment of glioblastoma

Recent evidence has implicated microRNA-219 (miR-219) in regulation of gene contributed in glioblastoma (GBM) pathogenesis. This study aimed to prepare miR-219 in chitosan (CS) nanoparticles (NPs), characterize and investigate their efficacy on human GBM cell line (U87 MG). NPs were prepared using i...

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Hlavní autoři: Rawan Alswailem, Fulwah Yahya Alqahtani, Fadilah Sfouq Aleanizy, Bahauddeen M. Alrfaei, Mohammad Badran, Qamraa Hamad Alqahtani, Hosam Gharib Abdelhady, Ibrahim Alsarra
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis Group 2022-12-01
Edice:Artificial Cells, Nanomedicine, and Biotechnology
Témata:
Glioblastoma
microRNA
Chitosan
Nanoparticles
gene delivery
microRNA-219
On-line přístup:https://www.tandfonline.com/doi/10.1080/21691401.2022.2092123
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