Fatty Acid Oxidation Promotes Apoptotic Resistance and Proinflammatory Phenotype of CD4+ Tissue-resident Memory T cells in Crohn’s DiseaseSummary

Background & Aims: As the most abundant memory T cells and major source of tumor necrosis factor α in the intestinal mucosa of Crohn’s disease (CD) patients, CD4+ tissue-resident memory T (TRM) cells play a critical role in CD pathogenesis. We investigated the role of metabolic reprogramming in...

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Detalhes bibliográficos

Principais autores:	Guanzhan Liang, Junfeng Huang, Jing Chen, Xiaofeng Wen, Ruibing Li, Hanlin Xie, Zongjin Zhang, Zexian Chen, Yongle Chen, Zhenyu Xian, Xiaowen He, Jia Ke, Lei Lian, Ping Lan, Xianrui Wu, Tuo Hu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-01-01
coleção:	Cellular and Molecular Gastroenterology and Hepatology
Assuntos:	Fatty Acid Oxidation Crohn’s Disease CD4+ Tissue-resident Memory T Cell Proinflamatory Phenotype
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2352345X24000420
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