A novel protein B2URF3 from Akkermansia muciniphila increased by intermittent fasting alleviates vascular calcification

Abstract Vascular calcification (VC) is a major contributor to cardiovascular morbidity and mortality, yet effective therapies are lacking. Here, we show that alternate-day intermittent fasting (IF1:1) attenuates vitamin D-induced VC in mice, whereas a 5:2 regimen is ineffective. The protective effe...

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Egile Nagusiak:	Shi-Yu Zeng, Jiang-Hua Liu, Ying-Ying Xiang, Zhao-Lin Zeng, Zhi-Bo Zhao, Jie zheng, Yi-Fu Liu, Zhi-Rou Lin, Yi-Yi Wang, Chun-Gu Hong, Ling Jin, Guo-Qiang Zhu, Yi-Wei Liu, Xin Wang, Xiao-Xue Li, Zhe Guan, Zhen-Xing Wang, Ting Sun, Hui Xie
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2026-01-01
Saila:	Journal of Nanobiotechnology
Gaiak:	Intermittent fasting Gut-vascular axis Akkermansia muciniphila Extracellular vesicles Vascular calcification
Sarrera elektronikoa:	https://doi.org/10.1186/s12951-025-03948-0
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