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Modulating the extracellular matrix to treat wound healing defects in Ehlers-Danlos syndrome

Summary: Classic Ehlers-Danlos syndrome (cEDS) is a genetic disorder of the connective tissue that is characterized by mutations in genes coding type V collagen. Wound healing defects are characteristic of cEDS and no therapeutic strategies exist. Herein we describe a murine model of cEDS that pheno...

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Principais autores: Kindra M. Kelly-Scumpia, Maani M. Archang, Prabhat K. Purbey, Tomohiro Yokota, Rimao Wu, Jackie McCourt, Shen Li, Rachelle H. Crosbie, Philip O. Scumpia, Arjun Deb
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-09-01
Serier:iScience
Fag:
medicine
cell biology
Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004224019011
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