Patient derived xenograft models of hormone receptor positive and HER2 negative breast cancer from Indian patients

Abstract Limited success has been achieved in the development of patient-derived xenografts (PDX) models of hormone receptor-positive (HR+), Human Epidermal growth factor Receptor 2-negative (HER2-negative) metastatic breast cancers that are resistant to hormone therapy (HT). We aimed to establish a...

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Autori principali:	Khusbhoo A. Gandhi, Rohan Chaubal, Elizabeth Talker, Jaya Chitra Aadhi, Shwetali Pandey, Rushikesh Mukhare, Anushree Kadam, Ankita Singh, Mamta Gurav, Pallavi Parab, Yogesh Kembhavi, Rahul Thorat, Anbarasan Sekar, Seema Gulia, Kunal Gala, Nitin Shetty, Shalaka Joshi, Suyash Kulkarni, Tanuja Shet, Sudeep Gupta
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Portfolio 2025-11-01
Serie:	Scientific Reports
Soggetti:	Patient derived xenografts ER PR HER2 Hormone therapy-resistant Breast cancer
Accesso online:	https://doi.org/10.1038/s41598-025-22361-z
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