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Posterior reversible encephalopathy syndrome across 22 VEGF-pathway inhibitors in the FDA adverse event reporting system: reporting patterns and reporting-interval characteristics

ObjectivesPosterior reversible encephalopathy syndrome (PRES) is a rare but potentially severe complication of VEGF-pathway inhibition. A recent FAERS analysis supported PRES as a probable class effect of angiogenesis inhibitors but found no association with continuous VEGFR affinity, did not formal...

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Principais autores: Ji Li, Yan Cheng, Yunzhou Yang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-07-01
Serier:Frontiers in Pharmacology
Fag:
disproportionality analysis
FAERS
fruquintinib
pharmacovigilance
posterior reversible encephalopathy syndrome
ramucirumab
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2026.1887454/full
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