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Identification of candidate driver genes in common focal chromosomal aberrations of microsatellite stable colorectal cancer.

Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide. Chromosomal instability (CIN) is a major driving force of microsatellite stable (MSS) sporadic CRC. CIN tumours are characterised by a large number of somatic chromosomal copy number aberrations (SCNA) that frequently affect onco...

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Autores principales: George J Burghel, Wei-Yu Lin, Helen Whitehouse, Ian Brock, David Hammond, Jonathan Bury, Yvonne Stephenson, Rina George, Angela Cox
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2013-01-01
Colección:PLoS ONE
Acceso en línea:https://doi.org/10.1371/journal.pone.0083859
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