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A critical evaluation of protein kinase regulation by activation loop autophosphorylation

Phosphorylation of proteins is a ubiquitous mechanism of regulating their function, localization, or activity. Protein kinases, enzymes that use ATP to phosphorylate protein substrates are, therefore, powerful signal transducers in eukaryotic cells. The mechanism of phosphoryl-transfer is universall...

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Bibliographic Details
Main Authors: Ronja Reinhardt, Thomas A Leonard
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications Ltd 2023-07-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/88210
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