Distribution of the cytochrome P450 CYP2C8*2 allele in Brazzaville, Republic of Congo
Background: Cytochrome P450 (CYP) enzymes are essential in the metabolism of most drugs used today. Single nucleotide polymorphism(s) occurring in CYP genes can adversely affect drug pharmacokinetics, efficacy, and safety. Individuals carrying the CYP2C8*2 c.805A > T (CYP2C8*2; rs11572103) allele ha...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2019-08-01
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| Schriftenreihe: | International Journal of Infectious Diseases |
| Online-Zugang: | http://www.sciencedirect.com/science/article/pii/S1201971219302061 |
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