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Efficient delivery of small RNAs to podocytes in vitro by direct exosome transfection

Abstract Background Podocytes are a crucial component of the glomerular filtration barrier, and changes in their 3D structure contribute to over 80% of chronic kidney disease (CKD) cases. Exosomal small RNAs play a key role in cell–cell communication in CKD and may serve as nanocarriers for deliveri...

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Autori principali: Tim Lange, Luzia Maron, Claudia Weber, Doreen Biedenweg, Rabea Schlüter, Nicole Endlich
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2025-05-01
Serie:Journal of Nanobiotechnology
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Accesso online:https://doi.org/10.1186/s12951-025-03426-7
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