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Performance of P16INK4a immunocytochemical stain in facilitating cytology interpretation of HSIL for HPV-positive women aged 50 and above

BackgroundFew articles have focused on the cytological misinterpretation of high-grade squamous intraepithelial lesion (HSIL). Due to estrogen deficiency, cervical epithelial cells in postmenopausal women tend to show atrophic change that looks like HSIL on Papanicolaou-stained cytology slides, resu...

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Principais autores: Jun Hou, Hui Du, Chun Wang, Fangbin Song, Xinfeng Qu, Ruifang Wu
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-05-01
Serier:Frontiers in Oncology
Fag:
P16 immunocytochemical stain
atrophy
cytology
high-grade squamous intraepithelial lesion (HSIL)
menopause
Online adgang:https://www.frontiersin.org/articles/10.3389/fonc.2024.1332172/full
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