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Tyrosine kinase ETK/BMX is up-regulated in bladder cancer and predicts poor prognosis in patients with cystectomy.

Deregulation of the non-receptor tyrosine kinase ETK/BMX has been reported in several solid tumors. In this report, we demonstrated that ETK expression is progressively increased during bladder cancer progression. We found that down-regulation of ETK in bladder cancer cells attenuated STAT3 and AKT...

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Detalhes bibliográficos
Principais autores: Shengjie Guo, Feng Sun, Zhiyong Guo, Wei Li, Alan Alfano, Hegang Chen, Clara E Magyar, Jiaoti Huang, Toby C Chai, Shaopeng Qiu, Yun Qiu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-03-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3049795?pdf=render
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