A Conjugate between Lqh-8/6, a Natural Peptide Analogue of Chlorotoxin, and Doxorubicin Efficiently Induces Glioma Cell Death

Natural peptides isolated from animal venoms generally target cell surface receptors with high affinity and selectivity. On many occasions, some of these receptors are over-expressed in cancer cells. Herein, we identified Lqh-8/6 as a natural peptide analog of chlorotoxin, a proven and useful compou...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Lucie Dardevet, Feten Najlaoui, Sonia Aroui, Mayeul Collot, Céline Tisseyre, Michael W. Pennington, Jean-Maurice Mallet, Michel De Waard
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-10-01
Schriftenreihe:	Biomedicines
Schlagworte:	chlorotoxin Lqh-8/6 glioma cells apoptosis doxorubicin conjugation
Online-Zugang:	https://www.mdpi.com/2227-9059/10/10/2605
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