Concomitant cytomegalovirus DNAemia is associated with sustained TNF-α elevation in HIV/AIDS: a multivariable and longitudinal analysis of immune restoration

Abstract Background Despite successful viral suppression with antiretroviral therapy (ART), incomplete immune reconstitution and chronic inflammation persist in people with HIV, contributing to an increased burden of non-AIDS-defining comorbidities. Emerging evidence points to cytomegalovirus (CMV)...

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Autori principali:	Yuansi Lao, Deling Lei, Min Fang, Yongtao Le, Qingmei Huang, Wuning Mo, Gaobin Teng, Zengfu Li, Qituan Jiang, Ming Zhou, Sheng Liang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2026-05-01
Serie:	BMC Infectious Diseases
Soggetti:	HIV/AIDS Cytomegalovirus co-infection Chronic inflammation TNF-α T-cell exhaustion Immune restoration
Accesso online:	https://doi.org/10.1186/s12879-026-13560-8
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