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Identification of LRP1+CD13+ human periosteal stem cells that require LRP1 for bone repair

Human periosteal skeletal stem cells (P-SSCs) are critical for cortical bone maintenance and repair. However, their in vivo identity, molecular characteristics, and specific markers remain unknown. Here, single-cell sequencing revealed human periosteum contains SSC clusters expressing known SSC mark...

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Bibliografiske detaljer
Principais autores: Youngjae Jeong, Lorenzo Deveza, Laura Ortinau, Kevin Lei, John R. Dawson, Dongsu Park
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical investigation 2024-11-01
Serier:JCI Insight
Fag:
Online adgang:https://doi.org/10.1172/jci.insight.173831
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