Design, Synthesis, and Evaluation of New Hybrid Derivatives of 5,6-Dihydro-4<i>H</i>-pyrrolo[3,2,1-<i>ij</i>]quinolin-2(1<i>H</i>)-one as Potential Dual Inhibitors of Blood Coagulation Factors Xa and XIa

Cardiovascular diseases caused by blood coagulation system disorders are one of the leading causes of morbidity and mortality in the world. Research shows that blood clotting factors are involved in these thrombotic processes. Among them, factor Xa occupies a key position in the blood coagulation ca...

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Hlavní autoři:	Anna A. Skoptsova, Athina Geronikaki, Nadezhda P. Novichikhina, Alexey V. Sulimov, Ivan S. Ilin, Vladimir B. Sulimov, Georgii A. Bykov, Nadezhda A. Podoplelova, Oleg V. Pyankov, Khidmet S. Shikhaliev
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2024-01-01
Edice:	Molecules
Témata:	5,6-dihydro-4<i>H</i>-pyrrolo[3,2,1-<i>ij</i>]quinolin-2-one thiazole anticoagulant activity dual activity inhibitor factor Xa
On-line přístup:	https://www.mdpi.com/1420-3049/29/2/373
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