Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs

Due to its antiangiogenic and anti-immunomodulatory activity, thalidomide continues to be of clinical interest despite its teratogenic actions, and efforts to synthesize safer, clinically active thalidomide analogs are continually underway. In this study, a cohort of 27 chemically diverse thalidomid...

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Bibliografske podrobnosti

Principais autores:	Megan L. Peach, Shaunna L. Beedie, Cindy H. Chau, Matthew K. Collins, Suzana Markolovic, Weiming Luo, David Tweedie, Christian Steinebach, Nigel H. Greig, Michael Gütschow, Neil Vargesson, Marc C. Nicklaus, William D. Figg
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2020-12-01
Serija:	Molecules
Teme:	angiogenesis cereblon docking structure–activity relationships thalidomide
Online dostop:	https://www.mdpi.com/1420-3049/25/23/5683
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