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Staufen2-mediated RNA recognition and localization requires combinatorial action of multiple domains

The Staufen family of RNA-binding proteins are conserved microtubule dependent mRNA transporter factors. Here the authors use biochemical and functional approaches to characterize the RNA-binding properties of mouse Staufen 2 and study the mRNA binding capacity of its two domains dsRBDs 1 and 2.

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Détails bibliographiques
Auteurs principaux: Simone Heber, Imre Gáspár, Jan-Niklas Tants, Johannes Günther, Sandra M. Fernandez Moya, Robert Janowski, Anne Ephrussi, Michael Sattler, Dierk Niessing
Format: Artigo
Langue:Inglês
Publié: Nature Portfolio 2019-04-01
Collection:Nature Communications
Accès en ligne:https://doi.org/10.1038/s41467-019-09655-3
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