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Coordination of autophagosome closure and release by the Alzheimer’s disease-associated protein BIN1

Summary: Autophagosome closure by the endosomal sorting complex required for transport (ESCRT) complex is a prerequisite for their dynamin 2 (DNM2)-dependent release from the recycling endosome and subsequent lysosomal clearance. However, the mechanism that coordinates autophagosome closure and rele...

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Autors principals: Jennifer E. Palmer, Claudia Puri, Ryan S. O’Rourke, Sung Min Son, Chun Sang, Yu-Wen Alvin Huang, David C. Rubinsztein
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2025-09-01
Col·lecció:Cell Reports
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S221112472501037X
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