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Evaluation of the immunomodulatory activity of thalidomide on tumor-associated macrophages in the 4T1 murine metastatic breast cancer model

ABSTRACT The present work evaluated the immunomodulatory effect of thalidomide (Thal) at different doses on tumor-associated macrophages (TAMs) using a mouse model of human breast cancer. Mice were inoculated with 4T1 cells in the left flank and treated with Thal once a day at concentrations of 50,...

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Principais autores: D.C. Reis, M.A. Rodrigues, S.G.B. Pinto, A.C. Araújo e Silva, G.V. Moreira, L.C. Campos, P.P. Campos, S.L. Fialho, M.T.P. Lopes, D.A. Gomes, R.C. Russo, E. Ferreira, G.D. Cassali
Format: Artigo
Sprog:Inglês
Udgivet: Universidade Federal de Minas Gerais, Escola de Veterinária 2021-12-01
Serier:Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Fag:
breast cancer
immunomodulation
thalidomide
inflammation
tumor-associated macrophages
Online adgang:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352021000701334&tlng=en
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