FGF19 Is Coamplified With CCND1 to Promote Proliferation in Lung Squamous Cell Carcinoma and Their Combined Inhibition Shows Improved Efficacy

Lung squamous cell carcinoma (LUSC) remains as a major cause of cancer-associated mortality with few therapeutic options. Continued research on new driver genes is particularly important. FGF19, a fibroblast growth factor, is frequently observed as amplified in human LUSC, which is also associated w...

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Detaylı Bibliyografya
Asıl Yazarlar:	Yanshuang Zhang, Tingyu Wu, Fan Li, Yirui Cheng, Qing Han, Xin Lu, Shun Lu, Weiliang Xia
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Frontiers Media S.A. 2022-04-01
Seri Bilgileri:	Frontiers in Oncology
Konular:	LUSC FGF19 FGFR4 CCND1 CDK4/6 amplification
Online Erişim:	https://www.frontiersin.org/articles/10.3389/fonc.2022.846744/full
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FGF19 Is Coamplified With CCND1 to Promote Proliferation in Lung Squamous Cell Carcinoma and Their Combined Inhibition Shows Improved Efficacy

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