A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission.

Hepatitis C virus (HCV) infection is a challenge to prevent and treat because of the rapid development of drug resistance and escape. Viral entry is required for initiation, spread, and maintenance of infection, making it an attractive target for antiviral strategies.Using genetic immunization, we p...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Isabel Fofana, Fei Xiao, Christine Thumann, Marine Turek, Laetitia Zona, Rajiv G Tawar, Fritz Grunert, John Thompson, Mirjam B Zeisel, Thomas F Baumert
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2013-01-01
Colecção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC3660333?pdf=render
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!