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Efficacy of Decitabine and Venetoclax as Salvage and Bridge Therapy to Haploidentical Hematopoietic Stem Cell Transplantation in a Multiresistant Acute Myeloid Leukemia Patient

Treatment of relapsed/refractory or elderly unfit acute myeloid leukemia (AML) is still challenging, and hypomethylating agents in combination with venetoclax, an oral selective BCL2 inhibitor, might be successfully used as salvage therapy. However, clinical trials evaluating the efficacy and safety...

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Principais autores: Bianca Serio, Valentina Giudice, Denise Morini, Roberto Guariglia, Rosa Vitolo, Paola Manzo, Maddalena Langella, Carmine Selleri
Format: Artigo
Sprog:Inglês
Udgivet: Karger Publishers 2022-06-01
Serier:Case Reports in Oncology
Fag:
acute myeloid leukemia
hypomethylating agents
bcl2 inhibitor
salvage therapy
hematopoietic stem cell transplantation
Online adgang:https://www.karger.com/Article/FullText/524952
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