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NKCC1 Deficiency in Forming Hippocampal Circuits Triggers Neurodevelopmental Disorder: Role of BDNF-TrkB Signalling

The time-sensitive GABA shift from excitatory to inhibitory is critical in early neural circuits development and depends upon developmentally regulated expression of cation-chloride cotransporters NKCC1 and KCC2. NKCC1, encoded by the <i>SLC12A2</i> gene, regulates neuronal Cl<sup>−</sup> homeostasi...

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Váldodahkkit: Jacek Szymanski, Liliana Minichiello
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2022-04-01
Ráidu:Brain Sciences
Fáttát:
Liŋkkat:https://www.mdpi.com/2076-3425/12/4/502
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