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The Antiepileptic Drug and Toxic Teratogen Valproic Acid Alters Microglia in an Environmental Mouse Model of Autism

Autism spectrum disorder (ASD), a neurodevelopmental condition affecting approximately 1 in 44 children in North America, is thought to be a connectivity disorder. Valproic acid (VPA) is a multi-target drug widely used to treat epilepsy. It is also a toxic teratogen as well as a histone deacetylase...

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Principais autores: Korawin Triyasakorn, Ubah Dominic Babah Ubah, Brandon Roan, Minsyusheen Conlin, Ken Aho, Prabha S. Awale
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-07-01
Serier:Toxics
Fag:
Online adgang:https://www.mdpi.com/2305-6304/10/7/379
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