Increasing donor kidney age significantly aggravates the negative effect of pretransplant donor-specific anti-HLA antibodies on kidney graft survival

Background and hypothesisThe presence of donor-specific anti-HLA antibodies before kidney transplantation (preDSAs) is associated with decreased graft survival. The hypothesis that increasing donor kidney age is negatively associated with the impact of preDSA on graft survival was investigated.Metho...

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Principais autores:	Michiel G. H. Betjes, Judith A. Kal-van Gestel, Dave Roelen, Marcia M. L. Kho, Sebastian Heidt, Annelies E. de Weerd, Jacqueline van de Wetering
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2025-04-01
Series:	Frontiers in Immunology
Assuntos:	age donor kidney antibody-mediated rejection donor-specific anti-HLA antibodies graft survival kidney transplantation
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574324/full
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