Transcription-coupled structural dynamics of topologically associating domains regulate replication origin efficiency

Abstract Background Metazoan cells only utilize a small subset of the potential DNA replication origins to duplicate the whole genome in each cell cycle. Origin choice is linked to cell growth, differentiation, and replication stress. Although various genetic and epigenetic signatures have been link...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Yongzheng Li, Boxin Xue, Mengling Zhang, Liwei Zhang, Yingping Hou, Yizhi Qin, Haizhen Long, Qian Peter Su, Yao Wang, Xiaodong Guan, Yanyan Jin, Yuan Cao, Guohong Li, Yujie Sun
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2021-07-01
Colecção:	Genome Biology
Assuntos:	Replication origin Topologically associating domain (TAD) Chromatin structure Transcription Super-resolution imaging STORM
Acesso em linha:	https://doi.org/10.1186/s13059-021-02424-w
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!