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Transcriptomic insights into the immune dynamics of wild-type mice challenged with SARS-CoV-2 Beta variant

Abstract Background Mice are useful small animal models to study the pathogenesis of SARS-CoV-2 infection. As the ancestral SARS-CoV-2 strains did not utilize murine Ace2 as a receptor, wild-type mice were not susceptible to the SARS-CoV-2 infection. Infection of human ACE2-expressing transgenic mic...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Hamid Reza Jahantigh, Amany Elsharkawy, Komal Arora, Chinonye Dim, Mukesh Kumar
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2026-01-01
Rangatū:Laboratory Animal Research
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s42826-025-00264-4
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