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AM-2201 Inhibits Multiple Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes

AM-2201 is a synthetic cannabinoid that acts as a potent agonist at cannabinoid receptors and its abuse has increased. However, there are no reports of the inhibitory effect of AM-2201 on human cytochrome P450 (CYP) or uridine 5′-diphospho-glucuronosyltransferase (UGT) enzymes. We evaluated the inhi...

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Príomhchruthaitheoirí: Ju-Hyun Kim, Soon-Sang Kwon, Tae Yeon Kong, Jae Chul Cheong, Hee Seung Kim, Moon Kyo In, Hye Suk Lee
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: MDPI AG 2017-03-01
Sraith:Molecules
Ábhair:
Rochtain ar líne:http://www.mdpi.com/1420-3049/22/3/443
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