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A linear DNA template-based framework for site-specific unnatural amino acid incorporation

Site-specific incorporation of unnatural amino acids (UNAAs) into proteins using an orthogonal translation system (OTS) has expanded the scope of protein-coding chemistry. The key factor affecting UNAA embedding efficiency is the orthogonality of the OTS. Compared to traditional cell systems, cell-f...

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Autors principals: Xinjie Chen, Yingying Liu, Jiaqi Hou, Yuan Lu
Format: Artigo
Idioma:Inglês
Publicat: KeAi Communications Co., Ltd. 2021-09-01
Col·lecció:Synthetic and Systems Biotechnology
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2405805X21000399
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