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Pirfenidone for the treatment of bronchiolitis obliterans syndrome related to chronic graft-versus-host disease

Abstract: Bronchiolitis obliterans syndrome (BOS) is a severe form of chronic graft-versus-host disease (cGVHD) following allogeneic hematopoietic cell transplant (HCT), with a 5-year survival rate of 40%. Currently, there is no curative therapy for BOS. Preclinical data suggest that pirfenidone, an...

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Bibliografski detalji
Glavni autori: Husham Sharifi, Carson Tyler Moss, Zayan Musa, Alexander Bell, Christian O’Donnell, Carlos Hernandez Borges, Efthymia Iliana Matthaiou, Laura Johnston, Craig J. Galban, Ajay Sheshadri, Gregory Yanik, Guang-Shing Cheng, Joe L. Hsu
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2025-10-01
Serija:Blood Advances
Online pristup:http://www.sciencedirect.com/science/article/pii/S2473952925003519
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