Population genomics and transcriptomics of Plasmodium falciparum in Cambodia and Vietnam uncover key components of the artemisinin resistance genetic background

Abstract The emergence of Plasmodium falciparum parasites resistant to artemisinins compromises the efficacy of Artemisinin Combination Therapies (ACTs), the global first-line malaria treatment. Artemisinin resistance is a complex genetic trait in which nonsynonymous SNPs in PfK13 cooperate with oth...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Sourav Nayak, Thomas J. Peto, Michal Kucharski, Rupam Tripura, James J. Callery, Duong Tien Quang Huy, Mathieu Gendrot, Dysoley Lek, Ho Dang Trung Nghia, Rob W. van der Pluijm, Nguyen Dong, Le Thanh Long, Ranitha Vongpromek, Huy Rekol, Nguyen Hoang Chau, Olivo Miotto, Mavuto Mukaka, Mehul Dhorda, Lorenz von Seidlein, Mallika Imwong, Xavier Roca, Nicholas P. J. Day, Nicholas J. White, Arjen M. Dondorp, Zbynek Bozdech
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Portfolio 2024-12-01
Sarja:	Nature Communications
Linkit:	https://doi.org/10.1038/s41467-024-54915-6
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