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Nebivolol ameliorates sepsis-evoked kidney dysfunction by targeting oxidative stress and TGF-β/Smad/p53 pathway

Abstract Sepsis is a potential fetal organ destruction brought on through an overzealous immunologic reaction to infection, causing severe inflammation, septic shock, and damage to different organs. Although there has been progress in the identification and controlling of clinical sepsis, the fatali...

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Principais autores: Rahma Tharwat Sabra, Amany Abdlrehim Bekhit, Nourhan Tharwat Sabra, Nadia Ahmed Abd El-Moeze, Moustafa Fathy
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Portfolio 2024-06-01
סדרה:Scientific Reports
נושאים:
Nebivolol
Sepsis
Nephrotoxicity
Fibrosis
TGF-β/Smad/p53
NF-kB
גישה מקוונת:https://doi.org/10.1038/s41598-024-64577-5
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