Study on the regulation of gastric cancer cell apoptosis by LACTB through mitochondrial autophagy pathway

Abstract This study aimed to determine whether β-lactamase-like protein (Lactamase-β, LACTB) influences apoptosis in gastric cancer cells by modulating mitochondrial autophagy through the PTEN-induced putative kinase 1 (PINK1) or Parkin pathway. Firstly, the expression level of LACTB in gastric canc...

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Auteurs principaux:	Wei Nie, Lihua Hu, Zhiqiang Yan, Qian Wang, Shui He, Xiaoqiang Gao, Fang Yang
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2025-07-01
Collection:	Scientific Reports
Sujets:	Gastric cancer β-lactamase-like protein Apoptosis Mitophagy PINK1/Parkin pathway
Accès en ligne:	https://doi.org/10.1038/s41598-025-06047-0
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