The response to influenza vaccination is associated with DNA methylation-driven regulation of T cell innate antiviral pathways

Abstract Background The effect of vaccination on the epigenome remains poorly characterized. In previous research, we identified an association between seroprotection against influenza and DNA methylation at sites associated with the RIG-1 signaling pathway, which recognizes viral double-stranded RN...

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Autores principales:	Hongxiang Fu, Harry Pickering, Liudmilla Rubbi, Ted M. Ross, Wanding Zhou, Elaine F. Reed, Matteo Pellegrini
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2024-08-01
Colección:	Clinical Epigenetics
Materias:	DNA methylation Influenza virus Influenza vaccine Targeted bisulfite sequencing RNA sequencing Cell-type deconvolution
Acceso en línea:	https://doi.org/10.1186/s13148-024-01730-x
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