Semaglutide reduces alcohol intake and relapse-like drinking in male and female ratsResearch in context

Summary: Background: Glucagon-like peptide1 receptor (GLP-1R) agonists have been found to reduce alcohol drinking in rodents and overweight patients with alcohol use disorder (AUD). However, the probability of low semaglutide doses, an agonist with higher potency and affinity for GLP-1R, to attenua...

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Bibliografiske detaljer

Principais autores:	Cajsa Aranäs, Christian E. Edvardsson, Olesya T. Shevchouk, Qian Zhang, Sarah Witley, Sebastian Blid Sköldheden, Lindsay Zentveld, Daniel Vallöf, Maximilian Tufvesson-Alm, Elisabet Jerlhag
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2023-07-01
Serier:	EBioMedicine
Fag:	GLP-1 Nucleus accumbens Gut-brain axis Addition Dopamine Reward
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2352396423002074
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