Osteopontin (OPN/SPP1), a Mediator of Tumor Progression, Is Regulated by the Mesenchymal Transcription Factor Slug/SNAI2 in Colorectal Cancer (CRC)

In colorectal cancer (CRC), disease-related death is closely linked to tumor aggressiveness and metastasis. Gene expression profiling of patient tumors has suggested that a more mesenchymal phenotype, present in about one-fourth of all patients, is associated with increased aggressiveness. According...

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Detalhes bibliográficos

Principais autores:	Katyana Amilca-Seba, Tuan Zea Tan, Jean-Paul Thiery, Lila Louadj, Sandrine Thouroude, Anaïs Bouygues, Michèle Sabbah, Annette K. Larsen, Jérôme A. Denis
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-05-01
coleção:	Cells
Assuntos:	colorectal cancer (CRC) epithelial–mesenchymal transition (EMT) Slug/<i>SNAI2</i> transcription factor osteopontin (OPN/SPP1)
Acesso em linha:	https://www.mdpi.com/2073-4409/11/11/1808
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