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The Expression of the Senescence-Associated Biomarker Lamin B1 in Human Breast Cancer

Senescence is a major response to cancer chemotherapy and has been linked to unfavorable therapy outcomes. Lamin B1 is a component of the nuclear lamina that plays a pivotal role in chromatin stability. Downregulation of lamin B1 represents an established biomarker for cellular senescence. However,...

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Principais autores: Tareq Saleh, Ahmad Alhesa, Mohammed El-Sadoni, Nisreen Abu Shahin, Elham Alsharaiah, Sofian Al Shboul, Heyam Awad, Sarah Bloukh, Mahmoud Al-Balas, Mohammad Alsalem, Bilal Azab, Tariq N. Aladily
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-02-01
Serier:Diagnostics
Fag:
lamin B1
immunohistochemistry
breast cancer
senescence
Online adgang:https://www.mdpi.com/2075-4418/12/3/609
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