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Demyelination and neurodegeneration early in experimental autoimmune encephalomyelitis contribute to functional deficits in the anterior visual pathway

Abstract Impaired visual function is a prevalent feature of optic neuritis (ON) in multiple sclerosis (MS). Abnormal visual evoked potential (VEP) findings of increased latencies, reduced amplitudes and abnormal waveforms as well as decreased retinal nerve fiber layer (RNFL) assessed by optical cohe...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Maria T. Sekyi, Micah Feri, Shane Desfor, Kelley C. Atkinson, Batis Golestany, Fernando Beltran, Seema K. Tiwari-Woodruff
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Portfolio 2024-10-01
Schriftenreihe:Scientific Reports
Schlagworte:
Multiple sclerosis
Optic nerve
Retinal ganglion cells
NanoString RNA
Visual evoked potentials
Optical coherence tomography
Online-Zugang:https://doi.org/10.1038/s41598-024-73792-z
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