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Influence of nitric oxide and cGMP on agonist-induced platelet adhesion: An in vitro study in platelets isolated from patients with liver cirrhosis

Background: Variceal bleeding, one of the major complica­tions of liver cirrhosis, is primarily due to platelet activation defect and secondarily due to coagulation defects. Platelet adhesion is the key event in hemostasis. Since nitric oxide (NO) related stress is known to influence platelet functi...

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Principais autores: Annie-Jeyachristy Sam, Arumugam Geetha, Rajagopal Surendran, Subburayan Kumar Jeevan, Sarangapani Arulprakash
Formato: Artigo
Idioma:Inglês
Publicado em: Society of Medical Biochemists of Serbia, Belgrade 2013-01-01
coleção:Journal of Medical Biochemistry
Assuntos:
platelet adhesion
liver cirrhosis
cytosolic calcium
cgmp nitric oxide
Acesso em linha:https://scindeks-clanci.ceon.rs/data/pdf/1452-8258/2013/1452-82581301059A.pdf
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