Iron-catalyzed [4 + 2] annulation of amidines with α,β-unsaturated ketoxime acetates toward 2,4,6-trisubstituted pyrimidines

An iron-catalyzed [4 ​+ ​2] annulation of amidines with α,β-unsaturated ketoxime acetates is described. This strategy employs amidines as CN units and provides a new protocol for the construction of 2,4,6-trisubstituted pyrimidines under batch and continuous flow conditions in moderate to good yield...

Volledige beschrijving

Bibliografische gegevens

Hoofdauteurs:	Qinghuan Wu, Luchao Li, Binyan Xu, Jie Sun, Dong Ji, Yuguang Li, Lei Shen, Zheng Fang, Jindian Duan, Beining Chen, Kai Guo
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	KeAi Communications Co. Ltd. 2023-05-01
Reeks:	Green Synthesis and Catalysis
Onderwerpen:	Annulation Amidines Ketoxime acetates Pyrimidines Iron
Online toegang:	http://www.sciencedirect.com/science/article/pii/S2666554923000017
Tags:	Voeg label toe Geen labels, Wees de eerste die dit record labelt!