Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria

Drp1 is the master regulator of mitochondrial fission, which has important impact on cellular functions. Here, Yang et al identified evolutionarily conserved proteins Clueless and its homolog CLUH as key regulators of Drp1 that function via translation of Drp1 receptors MiD49 and Mff.

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Huan Yang, Caroline Sibilla, Raymond Liu, Jina Yun, Bruce A. Hay, Craig Blackstone, David C. Chan, Robert J. Harvey, Ming Guo
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2022-03-01
Цуврал:	Nature Communications
Онлайн хандалт:	https://doi.org/10.1038/s41467-022-29071-4
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!