Heritability and Genome-Wide Association Analyses of Serum Uric Acid in Middle and Old-Aged Chinese Twins

Serum uric acid (SUA), as the end product of purine metabolism, has proven emerging roles in human disorders. Here based on a sample of 379 middle and old-aged Chinese twin pairs, we aimed to explore the magnitude of genetic impact on SUA variation by performing sex-limitation twin modeling analyses...

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Bibliographic Details

Main Authors:	Weijing Wang, Dongfeng Zhang, Chunsheng Xu, Yili Wu, Haiping Duan, Shuxia Li, Qihua Tan
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2018-03-01
Series:	Frontiers in Endocrinology
Subjects:	Chinese twins gene-based test genome-wide association study heritability serum uric acid
Online Access:	http://journal.frontiersin.org/article/10.3389/fendo.2018.00075/full
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