Adenoviral-mediated correction of methylmalonyl-CoA mutase deficiency in murine fibroblasts and human hepatocytes

<p>Abstract</p> <p>Background</p> <p>Methylmalonic acidemia (MMA), a common organic aciduria, is caused by deficiency of the mitochondrial localized, 5'deoxyadenosylcobalamin dependent enzyme, methylmalonyl-CoA mutase (MUT). Liver transplantation in the absence of gross hepatic dysfunction provides...

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Detalhes bibliográficos

Principais autores:	Korson Mark, Sloan Jennifer, Dorko Kenneth, Tsai Matthew S, Chandler Randy J, Freeman Richard, Strom Stephen, Venditti Charles P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2007-04-01
coleção:	BMC Medical Genetics
Acesso em linha:	http://www.biomedcentral.com/1471-2350/8/24
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