Cullin 3 mitigates nonesterified fatty acid–induced oxidative stress in mammary epithelial cells: Involvement of BCL2/BECN1 and autophagy

ABSTRACT: High nonesterified fatty acid (NEFA) concentrations in cows with clinical ketosis lead to metabolic dysfunction in mammary cells, resulting in oxidative stress. Studies have shown that autophagy is impaired in the mammary glands of ketotic cows, and enhancing autophagy mitigates oxidative...

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Bibliografische gegevens

Hoofdauteurs:	Yifei Dong, Wenwen Gao, Kai Liu, Cai Lin, Muhammad Usman, Juan J. Loor, Guojin Li, Liguang Cao, Zifeng Yang, Jianchun Luo, Depeng Li, Qianwen Sun, Lin Lei, Xiliang Du, Yuxiang Song, Guowen Liu, Xinwei Li
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2025-04-01
Reeks:	Journal of Dairy Science
Onderwerpen:	autophagy clinical ketosis CUL3 oxidative stress
Online toegang:	http://www.sciencedirect.com/science/article/pii/S0022030225000797
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