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Association of the rs1800629 polymorphism in the TNF-α gene with nephrotic syndrome development: evidence from an updated meta-analysis

Abstract Introduction Despite its clinical significance, the precise pathogenesis of nephrotic syndrome (NS) remains elusive, with genetic factors and immune dysregulation implicated in disrupting glomerular filtration. Among these factors, TNF-α gene polymorphisms, such as the -308 G/A (rs1800629)...

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Principais autores: Raphael Enrique Tiongco, Neil David Cayanan, Michael John Dominguez, Ma. Theresa Mae Doctora, Julie Ann Mercado
פורמט: Artigo
שפה:Inglês
יצא לאור: SpringerOpen 2025-07-01
סדרה:Egyptian Pediatric Association Gazette
נושאים:
Nephrotic syndrome
TNF-alpha
-308 G/A
rs1800629
Asian
Meta-analysis
גישה מקוונת:https://doi.org/10.1186/s43054-025-00396-1
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