Use of gain-of-function suppressor screening to elucidate Candida albicans Cdr1 efflux mechanism, inhibition, and drug resistance
The ATP-binding cassette (ABC) transporter Cdr1 is a key mediator of antifungal drug resistance in Candida albicans, a major pathogen responsible for invasive candidiasis. Cdr1 belongs to the pleiotropic drug resistance (PDR) ABC transporter subfamily, exhibits broad substrate specificity, and plays...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2025-12-01
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| Col·lecció: | Frontiers in Microbiology |
| Matèries: | |
| Accés en línia: | https://www.frontiersin.org/articles/10.3389/fmicb.2025.1721050/full |
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