Fasciclin 2 functions as an expression-level switch on EGFR to control organ shape and size in Drosophila.
Fasciclin 2 (Drosophila NCAM) is a homophilic Cell Adhesion Molecule expressed at moderate levels in the proliferating epithelial cells of imaginal discs, where it engages EGFR in a cell autonomous auto-stimulatory loop that promotes growth along larval development. In addition, Fasciclin 2 is expre...
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| 主要作者: | |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science (PLoS)
2024-01-01
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| 叢編: | PLoS ONE |
| 在線閱讀: | https://doi.org/10.1371/journal.pone.0309891 |
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