Mechanistic Insights and Potential Therapeutic Approaches in PolyQ Diseases via Autophagy

Polyglutamine diseases are a group of congenital neurodegenerative diseases categorized with genomic abnormalities in the expansion of CAG triplet repeats in coding regions of specific disease-related genes. Protein aggregates are the toxic hallmark for polyQ diseases and initiate neuronal death. Au...

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Bibliografski detalji

Glavni autori:	Mukul Jain, Nil Patil, Gholamreza Abdi, Maryam Abbasi Tarighat, Arifullah Mohammed, Muhammad Rajaei Ahmad Mohd Zain, Khang Wen Goh
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2023-01-01
Serija:	Biomedicines
Teme:	autophagy polyQ neurons neurodegenerative diseases Huntington’s diseases
Online pristup:	https://www.mdpi.com/2227-9059/11/1/162
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